He is responsible for assay development and screening of early drug discovery projects including high content screening with special interest in targeting the ubiquitin system.
High content screening assays.
High content screening hcs in cell based systems uses living cells as tools in biological research to elucidate the workings of normal and diseased cells.
High content screening is a combination of modern cell biology with all its molecular tools with automated high resolution microscopy and robotic handling.
Using cell painting multiplex techniques you can even monitor multiple nodes in a cellular pathway.
High content screening hcs also known as high content analysis hca is a method that is used in drug discovery to identify substances that alter the phenotype of a cell in a desired manner.
Before this he worked as a postdoc and was awarded his phd by the max planck institute of biochemistry which focused on ubiquitin and ubiquitin like proteins.
Explore our high content screening platforms that are designed to provide exceptional resolution for subcellular detection automated detection and phenotyping with intact fixed or live cells.
High content screening assays of cell signalling physiology and function can all be studied using a high content analysis approach and perkinelmer offers a range of solutions to enable you to develop perform and analyze your cellular assays with ease.
Chemdiv has implemented high content based assays for high throughput screening and compound validation with a primary focus on disease process ontologies and mechanisms.